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C2 DOMAINS
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DeCS
Descriptor
English
:
C2 Domains
Descriptor
Spanish
:
Dominios C2
Descriptor
Portuguese
:
Domínios C2
Synonyms
English
:
C2 Domain
C2 Tensin type Domain
C2 Tensin-type Domain
C2 Tensin-type Domains
Domain, C2
Domain, C2 Tensin-type
Domains, C2
Domains, C2 Tensin-type
Tensin-type Domain, C2
Tensin-type Domains, C2
Tree Number:
G02.111.570.820.709.275.750.125
Definition
English
:
Protein modules that function in the targeting of
proteins
to CELL
MEMBRANES
. They consist of an eight-stranded anti-parallel beta-sandwich composed of a pair of four-stranded beta-sheets. This structural unit forms a pocket on the membrane-interacting face of the protein and co-ordinates the binding of 2 to 3
calcium
ions; however, not all
C2 domains
bind
calcium
. Examples of C2 domain-containing
proteins
include
PROTEIN KINASE C
and
PTEN PHOSPHOHYDROLASE.
History Note
English
:
2017
Allowable Qualifiers
English
:
DE
drug effects
GE
genetics
IM
immunology
PH
physiology
RE
radiation effects
Record Number:
56737
Unique Identifier:
D000070538
Occurrence in VHL
:
Similar:
DeCS